If you instantiate XPM NSUs in the RTL, you must define the aperture for each NSU in the XDC. The command below shows how to set an aperture on an NSU using an XDC constraint.
set_property APERTURES [list {0x201_0000_0000:0x201_0000_FFFF}] $nsu_0
No two NSUs can have the same addressing apertures, otherwise the tool can throw the error as shown below.
Figure 1. Aperture Error