The RF-ADC tile can be configured in several modes. The basic configuration options are available on the IP core configuration screen in the Vivado IDE and advanced operating modes can be configured using the RFdc driver API.
The RF-ADC is available in Quad or Dual configurations depending on the tile (see the Zynq UltraScale+ RFSoC Data Sheet: Overview (DS889) and the Zynq UltraScale+ RFSoC Data Sheet: DC and AC Switching Characteristics (DS926)).