Timing analysis of the synthesized design is useful to ensure that paths have the necessary constraints for effective implementation. The Vivado synthesis is timing-driven and adjusts the outputs based on provided constraints.
As more physical constraints, such as Pblocks and LOC constraints, are assigned in the design, the results of the timing analysis become more accurate, although these results still contain some estimation of path delay. The synthesized design uses an estimate of routing delay to perform analysis.
You can run timing analysis at this level to ensure that the correct paths are covered and for a more general idea of timing paths.
Important: Only timing analysis after implementation
(place and route) includes the actual delays for routing. Running timing analysis on the
synthesized design is not as accurate as running timing analysis on an implemented
design.