AMD supports the following operating systems on x86 and x86-64 processor architectures.
- Microsoft Windows Professional/Enterprise 10.0 20H2 Update; 10.0 21H1 Update; 10.0 21H2 Update; 10.0 22H2 Update
- Microsoft Windows 11.0 21H2 Update; 11.0 22H2 Update
- Red Hat Enterprise Workstation/Server 7.4, 7.5, 7.6, 7.7, 7.9, 8.3, 8.4, 8.5, 8.6, 8.7, 9.0 and 9.1 (64-bit), English/Japanese
- CentOS 7.4, 7.5, 7.6, 7.7, and 7.9 (64-bit), English/Japanese
- SUSE Linux Enterprise 12 SP4 and 15 SP2 (64-bit), English/Japanese
- Amazon Linux 2 AL2 LTS (64-bit)
- Ubuntu Linux 18.04.1 LTS; 18.04.2 LTS, 18.04.3 LTS; 18.04.4 LTS; 18.04.5 LTS; 18.04.6 LTS; and 20.04 LTS, 20.04.1 LTS, 20.04.2 LTS, 20.04.3 LTS, 20.04.4 LTS; 20.04.5 LTS; 22.04 LTS and 22.04.1 LTS (64-bit), English/Japanese